Table 2.
SZ (N = 174) | HCS (N = 638) | Statistics | ||||||
---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Effect size, d | t | p | ||
WMS-R indices | ||||||||
Memory indices | ||||||||
Verbal memory | 83.6 | 20.9 | 112.2 | 14.0 | −1.60 | t (810) = 21.15 | 2.0 × 10−79 | |
Visual memory | 85.4 | 18.6 | 105.2 | 9.6 | −1.33 | t (810) = 19.03 | 4.8 × 10−67 | |
Delayed recall | 79.3 | 20.3 | 109.5 | 12.0 | −1.81 | t (810) = 24.82 | 1.4 × 10−101 | |
General cognitive index | ||||||||
Attention/concentration | 92.6 | 15.3 | 110.1 | 12.8 | −1.24 | t (810) = 15.34 | 8.5 × 10−47 | |
MRI indices | ||||||||
Hippocampus | L | 2922.1 | 412.9 | 3140.1 | 340.9 | −0.58 | t (810) = 7.14 | 2.0 × 10−12 |
R | 2386.6 | 407.6 | 2576.9 | 327.8 | −0.51 | t (810) = 6.43 | 2.2 × 10−10 | |
Amygdala | L | 872.1 | 154.0 | 913.2 | 161.6 | −0.26 | t (810) = 3.01 | 2.7 × 10−3 |
R | 1142.0 | 200.2 | 1186.4 | 187.8 | −0.23 | t (810) = 2.73 | 6.6 × 10−3 | |
Thalamus | L | 3119.3 | 708.5 | 3299.8 | 673.2 | −0.26 | t (810) = 3.11 | 2.0 × 10−3 |
R | 2605.9 | 602.7 | 2752.0 | 556.1 | −0.25 | t (810) = 3.04 | 2.5 × 10−3 | |
Accumbens | L | 851.2 | 98.1 | 873.3 | 96.9 | −0.23 | t (810) = 2.67 | 7.7 × 10−3 |
R | 647.5 | 93.6 | 665.8 | 83.3 | −0.21 | t (810) = 2.49 | 1.3 × 10−2 | |
Caudate | L | 1799.1 | 361.2 | 1760.3 | 385.3 | 0.10 | t (810) = −1.18 | 0.24 |
R | 2371.2 | 380.6 | 2291.9 | 403.3 | 0.20 | t (810) = −2.30 | 2.2 × 10−2 | |
Putamen | L | 5914.8 | 578.1 | 5777.2 | 577.1 | 0.24 | t (810) = −2.79 | 5.4 × 10 −3 |
R | 5958.9 | 522.0 | 5761.8 | 507.9 | 0.38 | t (810) = −4.51 | 7.6 × 10 −6 | |
Pallidum | L | 1407.3 | 224.3 | 1255.0 | 202.2 | 0.71 | t (810) = −8.60 | 4.0 × 10 −17 |
R | 1212.6 | 171.5 | 1147.1 | 173.1 | 0.38 | t (810) = −4.42 | 1.1 × 10 −5 |
The unit for the MRI indices is mm3. Underline indicates p < 0.05
WMS-R Wechsler Memory Scale-Revised, MRI magnetic resonance imaging, SZ patients with schizophrenia, HCS healthy comparison subjects, SD standard deviation, L left, R right