Table 3.
Hippocampus | Amygdala | Thalamus | Accumbens | Caudate | Putamen | Pallidum | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
L | R | L | R | L | R | L | R | L | R | L | R | L | R | ||
Patients with schizophrenia | |||||||||||||||
Memory indices | |||||||||||||||
Verbal memory | r | 0.339 | 0.281 | 0.118 | 0.142 | 0.145 | 0.177 | 0.244 | 0.246 | 0.118 | 0.095 | 0.127 | 0.089 | −0.060 | 0.020 |
p | 4.6 × 10 −6 | 1.8 × 10 −4 | 6.1 × 10−2 | 5.5 × 10−2 | 5.5 × 10−2 | 1.9 × 10−2 | 1.17 × 10 −3 | 1.1 × 10 −3 | 0.12 | 0.21 | 0.10 | 0.24 | 0.43 | 0.79 | |
Visual memory | r | 0.361 | 0.410 | 0.196 | 0.079 | 0.236 | 0.270 | 0.170 | 0.192 | 0.033 | 0.005 | 0.039 | 0.013 | −0.161 | −0.012 |
p | 9.8 × 10 −7 | 2.0 × 10 −8 | 9.4 × 10−3 | 0.30 | 1.8 × 10−3 | 3.2 × 10 −4 | 2.5 × 10−2 | 1.1 × 10−2 | 0.67 | 0.94 | 0.61 | 0.86 | 3.4 × 10−2 | 0.87 | |
Delayed Recall | r | 0.333 | 0.310 | 0.099 | 0.084 | 0.170 | 0.194 | 0.255 | 0.270 | 0.031 | −0.002 | 0.075 | 0.041 | −0.120 | 0.002 |
p | 6.9 × 10 −6 | 3.2 × 10 −5 | 0.19 | 0.27 | 2.5 × 10−2 | 1.1 × 10−2 | 7.0 × 10 −4 | 3.1 × 10 −4 | 0.68 | 0.98 | 0.33 | 0.59 | 0.11 | 0.97 | |
General cognitive index | |||||||||||||||
Attention/Concentration | r | 0.252 | 0.229 | 0.123 | 0.076 | 0.093 | 0.163 | 0.088 | 0.231 | −0.013 | −0.034 | 0.082 | 0.035 | −0.033 | 0.080 |
p | 7.8 × 10 −4 | 2.4 × 10 −3 | 0.11 | 0.32 | 0.22 | 3.2 × 10−2 | 0.25 | 2.2 × 10 −3 | 0.86 | 0.65 | 0.28 | 0.65 | 0.66 | 0.29 | |
Healthy comparison subjects | |||||||||||||||
Memory indices | |||||||||||||||
Verbal memory | r | 0.020 | −0.024 | 0.004 | −0.023 | 0.042 | 0.038 | 0.011 | 0.055 | 0.002 | −0.015 | −0.031 | −0.042 | −0.008 | 0.029 |
p | 0.61 | 0.55 | 0.91 | 0.56 | 0.29 | 0.34 | 0.79 | 0.16 | 0.95 | 0.70 | 0.44 | 0.29 | 0.84 | 0.46 | |
Visual memory | r | −0.004 | 0.007 | −0.008 | 0.021 | −0.002 | 0.017 | −0.030 | 0.003 | −0.028 | −0.038 | 0.024 | −0.022 | 0.047 | 0.051 |
p | 0.93 | 0.87 | 0.84 | 0.60 | 0.96 | 0.67 | 0.45 | 0.93 | 0.48 | 0.34 | 0.55 | 0.58 | 0.24 | 0.20 | |
Delayed recall | r | 0.029 | 0.007 | −0.003 | 0.024 | 0.058 | 0.067 | 0.034 | 0.067 | 0.027 | 0.012 | −0.016 | −0.015 | 0.022 | 0.059 |
p | 0.47 | 0.85 | 0.94 | 0.54 | 0.14 | 9.0 × 10−2 | 0.39 | 9.0 × 10−2 | 0.49 | 0.77 | 0.70 | 0.71 | 0.57 | 0.14 | |
General cognitive index | |||||||||||||||
Attention/Concentration | r | −0.038 | −0.042 | 0.009 | −0.015 | −0.039 | −0.009 | −0.005 | −0.009 | −0.016 | 0.023 | 0.034 | 0.028 | <0.001 | 0.011 |
p | 0.34 | 0.28 | 0.82 | 0.71 | 0.32 | 0.81 | 0.89 | 0.83 | 0.68 | 0.56 | 0.39 | 0.49 | 1.00 | 0.78 |
Underline indicates p < 1.19 × 10−3 (0.05/42) for memory indices and p < 3.57 × 10−3 (0.05/14) for general cognitive index. WMS-R Wechsler Memory Scale-Revised, MRI magnetic resonance imaging, L left, R right, r Pearson correlation coefficient