Table 2. Clinical manifestations (n = 1,251a) and hospitalization of adverse effects following immunization, number of doses per event, and rate per 10,000 doses, in children up to 24 months of age. Araraquara, state of São Paulo, Brazil, 2000 to 2013.
Clinical manifestations/Hospitalization | Number of events | Number of doses per event | Rate per 10,000 dosesb | |
---|---|---|---|---|
Local | ||||
Pain | 189 | 4,040 | 2.5 | |
Nodule | 163 | 4,684 | 2.1 | |
Abscess | 33 | 23,138 | 0.4 | |
Lymphadenitis | 33 | 23,138 | 0.4 | |
Ulcer | 1 | 763,548 | 0.1 | |
Systemic | ||||
Headache | 1 | 763,548 | 0.1 | |
Nausea | 10 | 76,355 | 0.1 | |
Diarrhea | 23 | 33,198 | 0.3 | |
Vomiting | 54 | 14,140 | 0.7 | |
Cyanosis | 27 | 28,280 | 0.4 | |
Malaise | 23 | 33,198 | 0.3 | |
Irritability | 102 | 7,486 | 1.3 | |
Sleepiness | 44 | 17,353 | 0.6 | |
Myalgia | 7 | 109,078 | 0.1 | |
Exanthema | 46 | 16,599 | 0.6 | |
Jaundice | 1 | 763,548 | 0.1 | |
Parotitis | 20 | 38,177 | 0.3 | |
Fever | 344 | 2,220 | 4.5 | |
< 38°C | 51 | 14,971 | 0.7 | |
38|-|39,4°C | 196 | 3,896 | 2,6 | |
≥ 39.5°C | 68 | 11,229 | 0.9 | |
Hypotonic-hyporesponsive episode | 67 | 11,396 | 0.9 | |
Adenoiditis | 18 | 42,419 | 0.2 | |
Arthralgia | 1 | 763,548 | 0.1 | |
Hypersensitivity | 11 | 69,413 | 0.1 | |
Seizure | 25 | 30,542 | 0.3 | |
Loss of consciousness | 6 | 127,258 | 0.1 | |
Myelitis | 1 | 763,548 | 0.1 | |
Paresis | 1 | 763,548 | 0.1 | |
Hospitalization | 16 | 47,722 | 0.2 |
The 565 cases for which we had information presented 1,251 types of clinical manifestation.
Rate of AEFI for dose of any vaccine.