Table 2.
All patients (n = 82) |
ADPKD patients (n = 65) |
|||||||
---|---|---|---|---|---|---|---|---|
Univariable B (95% CI) | p value | Multivariable B (95% CI) | p value | Univariable B (95% CI) | p value | Multivariable B (95% CI) | p value | |
Intercept | −106.82 (−153.38 to −60.26) | <0.001 | −117.93 (−174.60 to −61.26) | <0.001 | −116.36 (−161.96 to −70.76) | <0.001 | −109.39 (−187.17 to −31.61) | 0.007 |
HtLVa | 18.15 (12.14 to 24.17) | <0.001 | 12.93 (6.66 to 19.21) | <0.001 | 18.97 (13.05 to 24.89) | <0.001 | 15.33 (8.56 to 22.11) | <0.001 |
Age | 0.12 (−0.22 to 0.45) | 0.50 | −0.10 (−0.59 to 0.39) | 0.69 | ||||
Female | 10.44 (1.56 to 19.31) | 0.02 | 11.84 (1.84 to 21.83) | 0.02 | ||||
Diagnosis ADPKD | −10.68 (−21.21 to −0.15) | 0.05 | NA | NA | ||||
Original study | 6.56 (−3.24 to 16.36) | 0.19 | 6.24 (−4.18 to 16.66) | 0.24 | ||||
HtKVa | −3.46 (−9.63 to 2.71) | 0.27 | ||||||
Renal function (eGFR) | −0.08 (−0.30 to 0.14) | 0.46 |
Liver and kidney volumes are height adjusted and log transformed. ADPKD: autosomal dominant polycystic kidney disease; PLD-Q: polycystic liver disease questionnaire; eGFR: estimated glomerular filtration rate using the Modification of Diet in Renal Disease formula; htKV: height-corrected kidney volume, htLV: height-corrected liver volume; CI: confidence interval.