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. 2018 Feb 6;8:2528. doi: 10.1038/s41598-018-20342-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect on spontaneous motor activity (A), motor coordination (B) and muscle strength (C) of rats. The decrease in distance traveled, time moving and stereotypic count and increased resting time was observed in cadmium-treated rats while improvement was observed in these rats treated with quercetin simultaneously. Tracking patterns were obtained from automated software ActiMot2 while monitoring the open field activity of rats in different treatment groups. Representative tracking pattern obtained has been shown in each group.Impairment in motor coordination and grip strength was observed in cadmium-exposed rats which also improved on simultaneous treatment with quercetin.Values are mean ± SEM of five rats in each group; Significantly differs (*p < 0.05, **p < 0.01); a-compared to control group; b-compared to cadmium exposed group.