Fig. 5.

Model of CegC3’s Glu-rich tail peptide bound to DotM153. a Surface representation of wild-type DotM153 (gray) in complex with the CegC3 peptide (magenta). See Methods section for modeling. b Zoom in into CegC3 (magenta) peptide interactions with DotM (gray). Interacting residues are shown in stick representation, color-coded blue and red for N and O atoms, and either magenta or gray for C atoms of the peptide and the protein, respectively. Panels 1–3 focus on the three areas, M1, M2, and M4, respectively, which were targeted for mutations, and for which binding was abrogated