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. 2018 Feb 6;8:2477. doi: 10.1038/s41598-018-20821-3

Figure 9.

Figure 9

Model of the effects of KD025 on 3T3-L1 adipocyte differentiation. KD025 inhibits adipocyte differentiation in 3T3-L1 cells, regulating the intermediate stage of this process. Differentiation is not promoted by the suppression of ROCK2 activity via KD025. This anti-adipogenic effect of KD025 might be mediated by the suppression of an unknown key pro-adipogenic regulator.