Table 2. Inclusion and exclusion criteria.

	Inclusion Criteria	Exclusion criteria
Database	- Search terms (See Table 1 for the search terms in PubMed and EBSCO)     - Year of publication between January 2000 and October 31st, 2016     - Language: English     - Peer-reviewed	N/A
Title / Abstract	The abstract or title of each article had to include a combination of the following keywords: pharmaceutical companies, healthcare providers, interaction, and effects, or variations to the preceding nouns.	- Explicitly mention only unilateral types of interaction or no clear distinction.     - Explicitly mention a different aim then investigating an effect of interaction.     - Non-empirical study.     - Non- quantitative study.     - Commentaries, reviews, opinion articles.
Full-texts	The article empirically investigates the effect of bilateral interaction between pharmaceutical companies and healthcare providers.	- Non-empirical studies.     - Non-quantitative studies.     - Studies on unilateral interaction or no clear distinction.     - Other stakeholders.     - Studies that only described the prevalence.     - Studies that describes no interaction.