Table 2. Correlations between marker expressions and clinicopathological variables with stromal PDGFRα, PDGFRβ, αSMA and vimentin (chi-square and Fisher's exact tests).

	PDGFRα S			PDGFRβ S			αSMA			Vimentin
	Low	High	P	Low	High	P	Low	High	P	Low	High	P
Age			0.431			0.443			0.341			0.594
<65	146	68		124	90		148	79		100	35
≥65	207	81		176	109		214	94		133	55
Gender			0.225			1.000			0.138			0.331
Female	109	55		97	64		123	47		51	25
Male	244	94		203	135		239	126		182	65
Weight-loss			0.659			0.119			0.602			0.808
<10%	319	132		275	173		327	153		211	80
>10%	34	17		25	26		35	20		22	10
Smoking status			0.842			0.100			0.726			0.041
Never	10	4		12	2		10	7		13	0
Present	222	98		184	132		233	109		146	63
Previous	121	47		104	65		119	57		74	27
ECOG			0.756			0.003			0.704			0.860
Normal	203	91		193	98		211	98		136	51
Slightly	125	48		91	82		125	65		85	33
In bed<50%	25	10		16	19		26	10		12	6
Histology			0.069			0.093			0.393			0.303
SCC	190	83		152	120		198	90		137	53
ADC	127	60		124	64		137	64		77	25
NOS	36	6		24	15		27	19		19	12
T-stage			0.159			0.840			0.505			0.888
T1a	49	22		45	26		53	21		25	11
T1b	68	20		54	34		63	31		42	15
T2a	127	49		101	71		128	61		86	36
T2b	42	29		46	25		48	27		33	14
T3	64	26		51	40		68	29		47	14
T4	3	3		3	3		2	4		0	0
N-stage			0.273			0.911			0.541			0.227
N0	237	105		202	136		248	116		159	64
N1	85	27		68	42		75	42		58	16
N2	31	17		30	21		39	15		16	10
P-stage			0.769			0.938			0.875			0.954
IA	93	34		79	47		94	40		53	21
IB	79	33		67	43		81	41		52	23
IIA	82	32		65	45		76	42		63	21
IIB	48	23		43	29		51	24		35	14
IIIA	51	27		46	35		60	26		30	11
Differentiation			0.129			0.250			0.688			0.917
Poor	153	59		131	78		160	70		98	39
Moderate	152	77		138	91		158	82		104	38
Well	48	13		31	30		44	21		31	13
Vascular invasion			0.520			0.906			0.012			0.236
No	292	119		244	163		306	130		200	72
Yes	60	29		55	35		55	42		33	18

Abbreviations: PDGFR, platelet derived growth factor; αSMA, alpha-smooth muscle actin; S, stroma; ECOG, Eastern cooperative oncology group; SCC, squamous cell carcinoma; ADC, adenocarcinoma; NOS, not otherwise specified