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. 2018 Jan 26;14(1):e1005944. doi: 10.1371/journal.pcbi.1005944

Table 6. Timing and memory usage to align Illumina and PacBio reads to human reference.

Illumina reads to Human reference
build index align result
time (min) memory (GB) time (min) memory (GB) aligned bases (Gbp) aligned reads
bwa-mem 96 4.5 197 11.2 38.46 263155221
bowtie2 51 18.6 163 4.0 38.00 258560571
nucmer4 36 45.1 146 45.5 36.71 250689492
PacBio reads to Human reference
build index align result
time (min) memory (GB) time (min) memory (GB) aligned bases (Gbp) aligned reads
blasr 40 29.4 1680 47.9 24.41 3836927
bwa-mem 96 4.5 1473 7.7 25.86 3820163
nucmer4 36 45.1 850 50.1 23.02 3784039