Table 2. Estimates of Multilocus Linkage Disequilibrium (LD) in Plasmodium vivax populations of the Southwest Pacific.
Population | Subpopulation | All haplotypes, all loci | Confirmed monoclonal haplotypes, all loci | ||||
---|---|---|---|---|---|---|---|
n | IAS | p | n | IAS | p | ||
Tetere 2004 | 21 | 0.012 | 0.18 | 0 | n.a. | n.d. | |
Tetere 2013 | 31 | 0.022 | 0.0042 | 16 | 0.033 | 0.0183 | |
Auki | 9 | 0.081 | 0.005 | 6 | 0.054 | 0.13 | |
Ngella | 165 | 0.026 | <0.00001 | 61 | 0.043 | <0.00001 | |
Bay | 32 | 0.041 | 0.0008 | 9 | 0.092 | 0.0052 | |
South | 17 | 0.068 | 0.0003 | 7 | 0.163 | 0.0005 | |
Channel | 29 | 0.074 | <0.00001 | 9 | 0.087 | 0.0053 | |
North | 73 | 0.038 | <0.00001 | 28 | 0.076 | <0.00001 | |
Anchor | 14 | 0.069 | 0.0009 | 8 | 0.046 | 0.0948 | |
Vanuatu | 22 | 0.157 | <0.00001 | 10 | 0.169 | <0.00001 | |
TOTAL | 248 | n.d. | n.d. | 93 | n.d. | n.d. |
Multilocus LD values from PNG and Tetere 2004 populations are published elsewhere [35]. Complete and unique haplotypes only were used for the analysis, by discarding all but one of the seven clonal haplotypes identified. n = number of haplotypes used in the analysis. IAS = Index of Association from LIAN analysis, MOI = multiplicity of infection, n.a. = not available due to sample size constraints, n.d. = not done.