Fig 1. Growth of malaria parasites in the liver and blood of mice following SPZ inoculation of Plasmodium yoelii with and without Schistosoma mansoni infection.
(A) Copy number of P. yoelii 18s RNA gene per 1×106mouse G3PDH gene measured at 42 h post SPZ inoculation. Female BALB/c mice (N = 6) infected with 50 S. mansoni-cercariae 10 weeks previously were challenged with 1,500 P. yoelii SPZ along with S. mansoni-non-infected controls. **P<0.01, Student’s two-tailed t-test, t = 4.362, df = 10. (B) Parasitaemia. Blood stage malaria parasites were monitored daily from day 2 to 8 post i.v. inoculation of 500 P. yoelii SPZ. (C) Percentage survival. Data from one representative experiment of three independent repeats are shown.