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Effect of R-DPN treatment of gonadectomized female and male rats on plasma corticosterone (panel A) and ACTH (panel B) levels in non-stress and stress (20 min. restraint) conditions after 12 daily injections of R-DPN. Each bar represents the mean +/- SEM of 6-8 individuals. *= p<0.05 vs non-stress control. @ indicates p<0.05 vs vehicle treated/stress group, # = p<0.05 vs similar group of opposite sex.
