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. Author manuscript; available in PMC: 2018 Feb 7.
Published in final edited form as: Physiol Behav. 2014 Mar 13;129:287–296. doi: 10.1016/j.physbeh.2014.03.004

Figure 4.

Figure 4

Effect of ICV treatment with an oxytocin receptor antagonist (OTA) and an ERβ agonist (R-DPN), given to gonadectomized female and male rats, on behaviors in the elevated plus maze. Animals were tested for 5 min in the EPM following 5 days of treatment with R-DPN. OTA was given 20 min prior to testing. A description of the results of 3 way and 2 way ANOVA are described in the results section. Panel A shows results for time in closed arm. Panel B shows results for Time in open arm. Panel C shows results for number of open arm entries. Panel D shows results for number of head dips. Panel E shows results for grooming behaviors. Each bar represents the mean +/- SEM of 6-8 individuals.. # indicates significant difference (p<0.05) versus vehicle-treated control following post hoc analysis. * indicates p<0.05 vs. central vehicle treated/ peripheral R-DPN group following post hoc analysis.