Table 4. Extended release amphetamine medications (10-15).
| Drug brand | Formulation (mg) | Dosing | Duration (hrs) | Comments |
|---|---|---|---|---|
| Adderall XR (amphetamine and dextroamphetamine) | Capsule: 5, 10, 15, 20, 25, 30 | Initial: 10 mg daily. Titration: 10 mg/week. Max: 30 mg/day | 8–12 | Can be sprinkled; side effects include insomnia, anorexia |
| Adzenys XR (amphetamine) | ODT: 3.1, 6.3, 9.4, 12.5, 15.7, 18.8 | Initial: 3.1 mg daily. Max: 18.8 mg (ages 6–12 years); 12.5 mg (ages 13–17 years) | 8–12 | Expensive |
| Dexedrine SR (amphetamine) | Capsule: 5, 10, 15 | Initial: 5 mg daily. Titration: 5 mg/week. Max:40 mg/day | 8–10 | Cannot be sprinkled; side effects: may see more anorexia, irritability |
| Vyvanse (lisdexamfetamine) | Capsule: 20, 30, 40, 50, 60, 70 | Initial: 20–30 mg daily. Titration: 10–20 mg/week. Max: 70 mg/day | 8–12 | – |
| Dyanavel XR (amphetamine) | Suspension: 2.5 mg/mL | Initial: 2.5–5 mg daily. Titration: 2.5–10 mg/week. Max: 20 mg/day | 8–12 | Contains d-and l-amphetamine in a 3.2:1 ratio, very expensive |
Adderall XR and Adzenys XR are amphetamines, Dexedrine SR, Vyvanse and Dyanavel XR are dextroamphetamines. Current long acting amphetamines/dextroamphetamines are approved for children ages 6 years and older. Drug brand names refer to United States brand names. hrs, hours; kg, kilograms; LA, long acting; max, maximum; mg, milligrams; mL, milliliters; ODT, oral disintegrating tablet; SR, sustained release; XR, extended release.