| Propofol |
Starting dose: 30–50 mg with increasing rate of 10 mg every 2 min or 1 mg/kg with increasing rate of 20 mg every 2 min (12) |
Delivering dose: 50–100 mL/60 min (12) |
(Single modality) starting dose: 1.5–3.0 ìg/mL; increasing rate 0.2–0.5, x times until the sedation level at the right observation window have been obtained; (Combined modality): starting dose of 1.5–3.0 ìg/mL; increasing rate 0.2–0.5, x times until the sedation level at the right observation window have been obtained (12) |
| Midazolam |
(Single Modality) starting dose: 0.03 mg/kg, observe for 2–5 min, increasing rate of 0.03 mg/kg after 2–5 min, and of 0.015 mg/kg after 5 min, until the sedation level at the right observation window have been obtained (12); (Combined modality): single bolus, starting dose of 0.05 mg/kg (12) |
– |
– |
| Dexmedetomidine |
Starting dose: 1.5 μg/kg over 10 minutes; maintenance infusion rate: 1.5 μg/kg/h |
– |
Starting dose: 1 μg/kg for 10 minutes, followed by an infusion at a rate of 1 μg/kg/hour (13) |
