Table 2.
Pathology findings from included studies
| Author | Polyp-free (n, %) | HP (n, %) | Non-AA (n, %) | AA (n, %) | CRC (n, %) | Definition of normal | Definition of AN |
|---|---|---|---|---|---|---|---|
| Guilera et al. [43] | 494 (68.6)# | 226 (31.4) | NS | NS | 1 | NS | |
| Kim et al. [44] | 1460 (83.7) | NS | 206 (11.8) | 78 (4.5) | NS | 2 | AA, CRC |
| Sedjo et al. [57] | 410 (68.3) | 54 (9.0) | 98 (16.3) | 38 (6.3) | 0 | 1 | AA |
| Kim et al. [45] | 1053 (80.0) | Excluded | 228 (17.3) | 35 (2.7) | Excluded | 2 | AA |
| Nam et al. [24] | 2877 (73.2) | NS | 960 (24.4) | 85 (2.2) | 11 (0.3) | 2 | AA, CRC |
| Stein et al. [46] | 384 (64.0) | NS | 176 (29.3) | 40 (6.7) | 0 | 2 | AA, CRC |
| Kim et al. [47] | 908 (68.7) | Excluded | 368 (27.8) | 46 (3.5) | Excluded | 2 | AA |
| Kim et al. [48] | 2456 (71.6)# | 744 (21.7) | 224 (6.5) | 6 (0.2) | 2 | AA, CRC | |
| Choe et al. [53] | 557 (46.2) | NS | 554 (45.9) | NS | 153 (12.7) | 3 | NS |
| Czwornog et al. [54] | 567 (73.4) | NS | 206 (26.6) | NS | NS | 1 | AA (any size) |
| Lipka et al. [55] | 612 (78.6) | NS | 167 (21.4) | NS | Excluded | 1 | NS |
| Yun et al. [49] | 16,163 (89.4)# | 1674 (9.3) | 248 (1.4) | Excluded | 3 | AA, CRA ≥ 3 | |
| Lee et al. [50] | 1080 (68.6)# | 494 (31.4) | NS | Excluded | 1 | NS | |
| Wang et al. [51] | 1379 (72.8) | 210 (11.1) | 305 (16.1)* | NS | 3 | NS | |
| Murphy et al. [52] | 3129 (87.9) | NS | 685 (19.2) | 143 (4.0) | 13 (0.4) | 2 | AA, CRC |
| Kim et al. [56] | 1555 (71.2) | NS | 629 (28.8) | NS | NS | 1 | NS |
| Wong et al. [35] | 7177 (63.2) | 853 (7.5) | 2604 (22.9) | 657 (5.8) | 71 (0.6) | 2 | AA |
Normal definition: 1: non-adenomatous; 2: polyps-free; 3: normal findings
HP hyperplastic polyp, AN advanced neoplasia, CRA colorectal adenoma, CRC colorectal cancer, AA advanced adenoma, adenoma measuring > 10 mm in diameter and/or with villous components and/or showing high grade dysplasia (32)
#Mixed with polys-free and HP (hyperplastic polyp)
*Mixed with any adenomas