Fig. 2.

LLLA attenuated PI-induced mechanical allodynia, but not heat hyperalgesia. Comparison of the effects of different wavelengths of LLLA on PI-induced nociceptive hypersensitivity. Red (RED-15) and near-infrared LLLA (NIR-15), which were applied daily for 15 min for 4 days from day 0 after PI, were tested. a, b Mechanical thresholds. c, d Heat thresholds. *p < 0.05, **p < 0.01 for RED-15 group vs. PI group, #p < 0.05, ##p < 0.01 for NIR-15 group vs. RED-15 group, +p < 0.05, ++p < 0.01 for NIR-15 group vs. RED-15 group through one-way ANOVA with Tukey’s post hoc test. N = 5 (control), N = 6 (PI), N = 7 (NIR-15), and N = 7 (RED-15)