Table 5.

Logistic regression model of corticosteroid therapy change

Variables	OR	95% CI		P value
Univariate Model
TBBx +	2.22	1.01	4.86	0.05
BAL +	0.58	0.24	1.42	0.23
Interactiona				0.71
Clinical:
Male	1.62	0.72	3.61	0.24
Age	1.00	0.97	1.03	0.86
Allogenicb	1.19	0.46	3.11	0.72
Reduced intensity conditioningc	0.71	0.29	1.75	0.46
GVHDd	1.25	0.58	2.70	0.57
Platelet count	1.0	0.99	1.00	0.95
Neutrophil count	0.99	0.89	1.09	0.81
Pulmonary Physiology:
FVCe	0.74	0.59	0.94	0.01
FEV1e	0.91	0.77	1.07	0.25
DLCOe	0.79	0.62	1.01	0.06
Radiology:
Diffuse air space disease	2.70	1.11	6.55	0.03
Diffuse Nodules	0.32	0.13	0.83	0.02
Bronchoscopy:
Antibiotic therapy prior to TBBxf	2.77	1.26	6.12	0.01
Antibiotic prior in daysg	1.01	0.96	1.06	0.73
No. of antibiotic prior to TBBxh	1.55	1.15	2.10	<0.01
No. of TBBx per procedure	1.10	0.79	1.52	0.57
Time from HSCT to TBBxi	0.83	0.71	0.97	0.02
Multivariate Model (AUC=0.81)	OR	95% CI		P value
TBBx +	3.12	1.18	8.23	0.02
BAL+	0.76	0.26	2.19	0.61
No. of antibiotic prior to TBBx	1.83	1.21	2.75	<0.01
FVCe	0.62	0.47	0.82	<0.001
Time from HSCT to TBBxi	0.85	0.71	1.02	0.08

^aInteraction btw BAL+ and TBBx+ OR=odds ratio

^bvs autologous

^cvs myeloablative conditioning

^dacute and/or chronic

^eper 10% increase in % predicted measure

^fantibiotics prior to procedure, yes vs no

^gper increase by 1

^hper increase by 1

ⁱper 100 days

Certain CT radiological features are not depicted with p>0.1