Table 7.
Logistic regression model of bronchoscopy related complications (n=600)
| Variable | OR | 95% CI | P value | |
|---|---|---|---|---|
| Univariate Model | N=600 | |||
| With TBBx | 3.27 | 1.70 | 6.31 | <0.001 |
| BAL negative | 1.03 | 0.51 | 2.07 | 0.94 |
| Clinical: | ||||
| Female | 2.07 | 1.09 | 3.94 | 0.03 |
| Age | 1.00 | 0.99 | 1.02 | 0.61 |
| Autologousa | 1.35 | 0.64 | 2.84 | 0.43 |
| Myeloablative conditioningb | 1.65 | 0.68 | 4.01 | 0.27 |
| GVHDc | 1.12 | 0.57 | 2.19 | 0.74 |
| Platelet count | 1.00 | 1.00 | 1.01 | 0.11 |
| Neutrophil count | 1.06 | 0.99 | 1.12 | 0.10 |
| Pulmonary physiology: | ||||
| FVCd | 1.23 | 1.02 | 1.48 | 0.03 |
| FEV1d | 1.16 | 1.00 | 1.34 | 0.05 |
| DLCOd | 1.29 | 1.05 | 1.59 | 0.01 |
| Bronchoscopy: | ||||
| Antibiotics, noe | 2.10 | 1.10 | 4.00 | 0.02 |
| No of antibiotics prior to bronchoscopy | 1.30 | 1.01 | 1.67 | 0.04 |
| Antibiotics prior in daysf | 1.08 | 1.01 | 1.15 | 0.03 |
| Multivariate Model (AUC=0.688) | OR | 95% CI | P value | |
| With TBBx | 3.33 | 1.63 | 6.79 | 0.001 |
| Myeloablativeb | 3.08 | 1.04 | 9.11 | 0.04 |
| FVCd | 1.02 | 1.00 | 1.04 | 0.05 |
vs allogenic
vs reduced intensity
acute and/or chronic
per 10% decrease in % predicted value
antibiotics prior to bronchoscopy, no vs yes
per 1 day decrease
Certain CT radiological features are not depicted with p>0.2