Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Semin Diagn Pathol. 2017 Nov 3;35(1):20–33. doi: 10.1053/j.semdp.2017.11.002

Figure 2. (A–C) Whipple’s disease.

Figure 2

(A) Small aggregates of macrophages are present in the lymph node sinuses and in the parenchyma forming loose epithelioid granulomas. (B) The macrophages have eosinophilic granular cytoplasm and occasional multinucleated giant cells are present. (C) The bacilli are positive with DPAS stain. (D) Histiocytosis following joint replacement: Sheets of polygonal histiocytes with abundant eosinophilic cytoplasm containing small black particles consistent with metal wear debris. (E–F) Silicone lymphadenopathy due to breast implant: (E) Aggregates of macrophages with abundant foamy, vacuolar cytoplasm are present within the lymph node. (F) The vacuoles are colorless and the silicone, where present, has a refractile quality and is non-polarizable.