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. Author manuscript; available in PMC: 2018 Jul 15.
Published in final edited form as: Nat Med. 2018 Jan 15;24(2):194–202. doi: 10.1038/nm.4464

Extended Data Fig. 4. Follow-up viabiity screening of V-9302 activity in human CRC cells.

Extended Data Fig. 4

In vitro multiplex assay (MultiTox Glo) of 15 colorectal cancer cell lines exposed to V-9302 (25 µM, 48 h). V-9302-dependent changes in the number of live cells (A, blue) and dead cells (B, red) relative to vehicle control; n = 3 independent experiments. (C) V-9302 Sulforhodamine B assay evaluating V-9302-dependent cell death in 9 colorectal cancer cell lines in vitro. Data for each assay relative to vehicle control; n = 3 independent experiments. Select mutational status (green squares) shown. All data is p < 0.05 as determined by Student’s t test relative to vehicle control unless otherwise indicated. n.s. = not statistically significant. Error bars represent ± std. dev.