After overexpression of miR-146a in B cells, mRNA levels of IL-1β (A), IL-6 (B) and IL-10 (C) were significantly decreased. However, after blockade of miR-146a by its inhibitor, the mRNA levels of IL-1β (D), IL-6 (E) and IL-10 (F) were significantly increased. The experiments were performed in triplicate. n=6–8. Data are presented as mean±SD. One-way ANOVA. * p < 0.05. Control: no RNA transfection.