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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Dec 27;1864(3):925–933. doi: 10.1016/j.bbadis.2017.12.035

Fig. 6. IRAK1 expression was inhibited by miR-146a in B cells after challenged with P. gingivalis LPS.

Fig. 6

miR-146a mimic could reduce the mRNA and protein levels of IRAK1 as detected by PCR (A) and ELISA (B). Also, addition of miR-146a inhibited TRAF6 expression in B cells at both mRNA (C) and protein level (D). Inhibition of miR-146a by its inhibitor significantly elevated both mRNA and protein levels of IRAK1 expression in B cells (E and F), as well as mRNA (G) and protein (H) levels of TRAF6 expression in B cells. The experiments were performed in triplicate. n=6–8. Data are presented as mean±SD. One-way ANOVA. * p < 0.05. Control: no RNA transfection.