Table 1.
Study population characteristics.
| Baseline Characteristic | |
|---|---|
| N | 123 |
| Age (years) | 59.9 ± 9.9 |
| Female (%) | 37 (30.1%) |
| African-American (%) | 21 (17.1%) |
| Body mass index (kg/m2) | 29.8 ± 5.5 |
| Obese (%) | 57 (46.3%) |
| Current smoker (%) | 29 (23.6%) |
| Diabetes (%) | 29 (23.6%) |
| Hypertension (%) | 103 (83.7%) |
| Previous myocardial infarction (%) | 49 (39.8%) |
| Recent acute coronary syndrome (%)a | 40 (32.5%) |
| Multivessel disease (%) | 77 (62.6%) |
| Recent revascularization procedure (%)b | 85 (69.1%) |
| Systolic blood pressure (mmHg) | 133 (22) |
| Diastolic blood pressure (mmHg) | 78 (12) |
| Total cholesterol (mg/dL) | 158 (55) |
| LDL cholesterol (mg/dL) | 86 (42) |
| HDL cholesterol (mg/dL) | 48 (17) |
| Triglycerides (mmol/L) | 97 (85) |
| ACE inhibitor or ARB use (%) | 76 (64.2%) |
| Beta-blocker use (%) | 100 (81.3%) |
| Statin use (%) | 115 (93.5%) |
| Aspirin use (%) | 120 (97.6%) |
| 81 mg/day (%) | 42 (34.1%) |
| 325 mg/day (%) | 78 (63.4%) |
| Clopidogrel use (%) | 99 (80.5%) |
ACE = angiotensin-converting enzyme, ARB=angiotensin receptor blocker, HDL=high density lipoprotein, LDL=low density lipoprotein
Data presented as mean ± standard deviation, median (interquartile range) or count (proportion).
a
21/123 (17.1%) and 19/123 (15.4%) were experiencing an unstable angina and myocardial infarction event, respectively, in the cardiac catheterization laboratory at the time of screening. At the time of the study visit, participants were confirmed to be clinically stable and chest pain free.
b
75/123 underwent a percutaneous coronary intervention and 10/123 underwent a coronary artery bypass grafting procedure between screening and the study visit.