Table 1.

Baseline Subject Characteristics

Characteristic	Study subjects (n=104)
Age, yr†	58.2 (20 – 83)
Male Gender	58 (55.8)
Smoking status
Never	52 (50)
Current	11 (10.6)
Former	41 (39.4)
Pack/years smoked	20.1 ± 20.4
Outpatient	91 (87.5)
HRCT: UIP designation
UIP pattern	7 (6.7)
Possible UIP	11 (10.6)
Inconsistent with UIP	86 (82.7)
Pulmonary Function Tests
FVC, L	2.8 ± 0.97
FVC, % predicted	70.2 ± 17.9
FEV1, L	2.2 ± 0.69
FEV1, % predicted	71.2 ± 17.2
TLC, L	4.3 ± 1.3
TLC, % predicted	70.2 ± 18.3
DLCO, mm/min/mmHg	14.6 ± 7.0
DLCO, % predicted	59.1 ± 22.6
Respiratory status
SpO2	96.3 ± 5
Supplemental oxygen at baseline	18 (17.3)
S:F ratio <315‡	9 (8.6)

Values presented as number (percentage) or mean ± standard deviation, unless otherwise noted. DLCO is reported corrected for hemoglobin, when available. DPLD = diffuse parenchymal lung disease; FVC = forced vital capacity; FEV1 = forced expiratory volume in the first second; TLC = total lung capacity; DLCO = diffusing capacity for carbon monoxide; SpO2 = pulse oximetric saturation; S:F ratio = SpO2 divided by fraction of inspired oxygen (FiO2).

^†Presented as mean (range).

^‡Correlates with PaO2:FiO2 ratio of 300.¹⁶