Table 2.
Univariate analysis of first cardiovascular hospital admission according to renal function status.
| Variable | All patients | Normal renal function | Chronic kidney disease | End-stage renal disease on dialysis | ||||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Male | 1.14 (0.78-1.7) | .51 | 1.39 (0.82-2.42) | .22 | 0.93 (0.46-1.92) | .87 | 1.61 (0.40-6.73) | .54 |
| Hypertension | 0.93 (0.64-1.34) | .72 | 0.69 (0.42-1.12) | .13 | 0.74 (0.35-1.57) | .47 | 1.79 (0.34-10.5) | .48 |
| Diabetes | 1.74 (1.2-2.54) | .002 | 1.50 (0.88-2.53) | .11 | 1.15 (0.58-2.3) | .74 | 1.70 (0.36-8.57) | .51 |
| Cancer | 0.53 (0.26-1.01) | .05 | 0.61 (0.24-1.36) | .29 | 0.30 (0.05-1.10) | .08 | 0 (0.18-∞) | .49 |
| Atrial fibrillation | 1.06 (0.67-1.67) | .82 | 1.45 (0.80-2.56) | .18 | 0.61 (0.24-1.44) | .25 | 1.97 (0.09-124) | >.99 |
| Heart failure | 2.08 (1.43-3.03) | <.001 | 1.84 (1.09-3.08) | .02 | 1.61 (0.80-3.25) | .18 | 1.65 (0.38-7.56) | .52 |
| Myocardial infarction | 1.43 (0.89-2.27) | .12 | 1.58 (0.86-2.82) | .13 | 1.32 (0.49-3.42) | .65 | 1.32 (0.19-10.44) | >.99 |
| Coronary artery disease | 1.42 (0.99-2.06) | .05 | 1.59 (0.98-2.59) | .05 | 0.99 (0.49-1.99) | >.99 | 1.08 (0.26-4.54) | >.99 |
| Peripheral artery disease | 2.70 (1.36-5.34) | .003 | 2.36 (0.59-8.42) | .16 | 1.37 (0.48-3.75) | .63 | 7.27 (0.76-366.79) | .09 |
| Cerebral vascular accident | 1.15 (0.65-1.98) | .59 | 1.57 (0.72-3.24) | .25 | 0.72 (0.25-1.86) | .52 | 0.43 (0.03-3.46) | .41 |
| Hemodialysis | 3.13 (1.37-7.18) | .004 | N/A | N/A | N/A | N/A | 1.07 (0.23-5.09) | >.99 |
| Peritoneal dialysis | 2.82 (0.74-10.69) | .09 | N/A | N/A | N/A | N/A | 0.93 (0.20-4.44) | >.99 |
| Angiotensin-converting-enzyme inhibitor | 1.86 (1.00-3.42) | .03 | 2.14 (0.99-4.48) | .04 | 1.63 (0.37-6.75) | .51 | 1.97 (0.09-124) | >.99 |
| Angiotensin receptor blockers | 0.94 (0.65-1.36) | .79 | 1.07 (0.66-1.74) | .81 | 0.78 (0.39-1.57) | .51 | 0.75 (0.16-3.38) | .74 |
| Beta-blocker | 1.37 (0.94-1.98) | .94 | 1.47 (0.90-2.43) | .13 | 1.19 (0.60-2.39) | .63 | 1.97 (0.48-8.53) | .35 |
| Calcium channel blocker | 0.98 (0.67-1.43) | .67 | 0.69 (0.39-1.18) | .17 | 0.93 (0.47-1.87) | .87 | 1.61 (0.40-6.67) | .54 |
| Metformin | 2.1 (1.11-3.86) | .01 | 3.23 (1.53-6.72) | .002 | 1.06 (0.26-3.73) | >.99 | N/A | N/A |
| Sulfonylurea | 1.2 (0.65-2.02) | .58 | 1.11 (0.45-2.52) | .83 | 1.99 (0.40-2.37) | >.99 | 0.95 (0.06-14.39) | >.99 |
| Glitazones | 0.92 (0.09-5.2) | >.99 | 1.84 (0.03-35.75) | .51 | 0.47 (0.01-4.87) | .66 | N/A | N/A |
| Insulin | 0.98 (0.27-2.95) | >.99 | 0 (0-8.93) | >.99 | 0.61 (0.10-2.59) | .55 | 0.95 (0.06-14.39) | >.99 |
| Spironolactone | 2.13 (1.28-3.52) | .002 | 2.23 (1.12-4.34) | .02 | 2.23 (0.94-5.29) | .06 | N/A | N/A |
| Thiazide | 1.72 (0.95-3.06) | .94 | 1.87 (0.82-4.06) | .10 | 1.55 (0.56-4.16) | .35 | 0.95 (0.01-78.40) | >.99 |
| Statins | 1.52 (1.05-2.19) | .02 | 1.49 (0.91-.2.43) | .09 | 01.37 (0.35-1.48) | .40 | 0 (0.21-4.10) | >.99 |
| Fenofibrate | 1.16 (0.79-1.67) | .46 | 0 (0-4.01) | .59 | 0.73 (0.24-3.22) | .40 | 0 (0.18-∞) | .49 |