Figure 3.

miR‐422a is positively associated with quadriceps strength and negatively associated with muscle loss in patients undergoing cardiac surgery. miR‐422a expression was determined in quadriceps samples from patients undergoing cardiac surgery. miR‐422a expression was positively associated with strength in men (n = 30, A) and with rectus femoris cross‐sectional area (RF_CSA) in men (n = 30, B). (C) In all patients, miR‐422a expression was lower in those who lost more than 10% RF_CSA in 7 days following surgery (n = 19 non‐wasting and 21 wasting patients). (D) In all patients, there was a negative association of miR‐422a expression and muscle loss over 7 days. Black circles represent male patients, and grey circles represent female patients.