Table 3.
Prognostic factors for overall survival (OS), univariate and multivariate analyses
| Prognostic factor | Univariate | Multivariate | ||
|---|---|---|---|---|
| P‐value | HR (95% CI) | P‐value | HR (95% CI) | |
| Age (years) | 0.834 | 0.996 (0.960–1.033) | ||
| Female gender | 0.132 | 0.494 (0.197–1.238) | 0.483 | 0.691 (0.247–1.937) |
| BMI (kg/m2) | 0.109 | 0.895 (0.781–1.025) | 0.720 | 0.972 (0.832–1.135) |
| Initial CEA (ng/mL) | 0.007 | 1.092 (1.025–1.164) | 0.014 | 1.130 (1.025–1.246) |
| Clinical TNM stage IIIa | 0.799 | 1.149 (0.394–3.349) | ||
| Radiotherapy | ||||
| Standard | Reference | |||
| Short course, 25 Gy | 0.697 | 0.783 (0.229–2.683) | ||
| Short course, 33 Gy | 0.539 | 1.369 (0.503–3.728) | ||
| Sarcopenia | 0.006 | 3.166 (1.396–7.180) | 0.013 | 3.558 (1.311–9.655) |
| Visceral obesity | 0.459 | 1.353 (0.608–3.013) | ||
| Intraoperative complication | 0.357 | 1.654 (0.567–4.822) | ||
| Anastomotic leak | 0.468 | 1.564 (0.468–5.233) | ||
| Prolonged admission | 0.103 | 1.946 (0.873–4.336) | 0.072 | 2.114 (0.935–4.777) |
| Length of stay | 0.822 | 1.010 (0.926–1.102) | ||
CEA, carcinoembryonic antigen.
a
Stage according to American Joint Committee on Cancer (AJCC) Cancer Staging Manual 7th edition.