Figure 5.
Effect of chronic obstructive pulmonary disease (COPD) and smoking status on survival in patients with non–small cell lung cancer treated with immune checkpoint inhibitors (ICIs). Shown are Kaplan-Meier curves comparing the progression-free survival (PFS) and overall survival (OS) from initiation of ICI therapy in patients with non–small cell lung cancer, analyzed by the presence of COPD (A and B) and by smoking status (C and D), and among former smokers with or without COPD (E and F). n = 125 patients in A–D and 92 patients in E and F. *P < 0.05. w/o = without.