Table 2.
Description of indications of testing for hereditary dispositions with fulfilled inclusion criteria
| Index patients | People seeking advice |
|---|---|
| In primary disease situation of breast carcinoma under primary chemotherapy | healthy relatives from informative families (with proven pathogenic mutation) |
| In primary disease situation of breast carcinoma at very early age of onset | healthy relatives with high mutation probability and deceased index patients |
| In secondary disease situation of ovarian carcinoma or breast carcinoma (study?) | caveat: appropriate time to consider r primary consultation |
| In disease-free interval after primary onset | non-directive consultation on consequences of testing |