Table 1.
Baseline Characteristics
| ≥65 years N=191 |
≥65 years N=173 |
P value | |
|---|---|---|---|
|
| |||
| Treatment Group N (%) | 1.000 | ||
| • OnabotulinumtoxinA | 100 (52.4) | 90 (52.0) | |
| • Neuromodulation | 91 (47.6) | 83 (48.0) | |
|
| |||
| Age Mean (SD) | 54.1 (7.9) | 72.9 (5.5) | ≥0.001 |
|
| |||
| BMI Mean (SD) | 33.0 (8.4) | 31.3 (7.9) | 0.034 |
|
| |||
| Ethnicity N (%) | 0.221 | ||
| • Non-Hispanic | 168 (88.0) | 159 (91.9) | |
| • Hispanic/Latina | 19 (9.9) | 9 (5.2) | |
| • Unknown/Not reported | 4 (2.1) | 5 (2.9) | |
|
| |||
| Race N (%) | 0.014 | ||
| • White | 151 (79.1) | 152 (87.9) | |
| • Black/African-Am | 29 (15.2) | 9 (5.2) | |
| • Asian | 1 (0.5) | 1 (0.6) | |
| • American Indian/Pacific Islander | 3 (1.6) | 2 (1.2) | |
| • Other | 5 (2.6) | 5 (2.9) | |
| • More than 1 race | 2 (1.0) | 1 (0.6) | |
| • Unknown | 0 (0) | 3 (1.7) | |
|
| |||
| Smoker N (%) | ≥0.001 | ||
| • No | 159 (83.2) | 165 (95.4) | |
| • Yes | 32 (16.8) | 8 (4.6) | |
|
| |||
| Functional Comorbidity Index, mean (SD) | 3.47 (2.3) | 3.98 (2.21) | 0.020 |
|
| |||
| Diabetes type 1 & 2 N (%) | 0.093 | ||
| • Don’t know | 1 (.5) | 0 (0) | |
| • No | 164 (85.9) | 137 (79.2) | |
| • Yes | 26 (13.6) | 36 (20.8) | |
|
| |||
| Degenerative Disc Disease N (%) | 0.625 | ||
| • Don’t know | 2 (1.0) | 1 (0.6) | |
| • No | 146 (76.4) | 127 (73.4) | |
| • Yes | 43 (22.5) | 45 (26.0) | |
|
| |||
| Recurrent UTIs (≥3 past year) N (%) | 0.759 | ||
| • No | 164 (85.9) | 151 (87.3) | |
| • Yes | 27 (14.1) | 22 (12.7) | |
|
| |||
| UUIE Mean (SD) | 5.11 (2.53) | 5.5 (2.8) | 0.178 |
|
| |||
| Sandvik Scorea Number (%) | 0.090 | ||
| • Slight | 1 (0.5) | 2 (1.2) | |
| • Moderate | 32 (16.8) | 20 (11.6) | |
| • Severe | 54 (28.3) | 36 (20.8) | |
| • Very Severe | 97 (50.8) | 111 (64.2) | |
| • Missing | 7 (3.7) | 4 (2.3) | |
|
| |||
| OABq-SFb Symptom Severity Mean (SD) | 76.2 (18.0) | 74.3 (18.6) | 0.370 |
|
| |||
| OABq-SFb Quality of Life Mean (SD) | 35.1 (21.7) | 40.2 (22.7) | 0.044 |
|
| |||
| Life Space Assessment Mean (SD) | 86.4 (28.9) | 82.2 (25.1) | 0.051 |
|
| |||
| HUI-3c Mean (SD) | 0.7 (0.3) | 0.7 (0.3) | 0.773 |
|
| |||
| UDId Mean (SD) | 60.9 (18.5) | 59.1 (16.7) | 0.533 |
|
| |||
| IIQe Mean (SD) | 58.8 (25.5) | 45.7 (26.4) | ≥0.001 |
a
scale of slight=1-2, moderate=3-6, severe=8-9, very severe=10-12
b
overall scores range 0-100; higher symptom severity scores indicate more symptoms, higher quality of life scores indicate better quality of life
c
represents overall health; score for death=0.00, score for perfect health=1.00
d
range 0-100, higher scores represent greater distress
e
range 0-100, higher scores indicate worse quality of life
f
t-tests used for continuous variables and chi-squared testing used for proportions