. Author manuscript; available in PMC: 2019 Jan 1.

Published in final edited form as: Am J Obstet Gynecol. 2017 Oct 12;218(1):111.e1–111.e9. doi: 10.1016/j.ajog.2017.10.006

Table 3.

Multivariable Model Results for ≥ 75% Reduction in UUI Episodes Over 6 Months

Outcome: ≥75% Reduction in UUI Episodes

Predictor	≥ 65 years Adjusted Odds Ratio (95% CI)	≥ 65 years Adjusted Odds Ratio (95% CI)	Predictor Main Effect p-value	Predictor x Age Interaction p-value	Predictor x Treatment Interaction p-value

Age ≥ 65
OnabotulinumtoxinA	3.31 (1.56, 7.02)	Reference	0.002	—	0.059
Neuromodulation	1.16 (0.51, 2.61)	Reference	0.721	—	0.059

Degenerative Disc Disease
OnabotulinumtoxinA	0.150 (0.059, 0.386)		<0.001	—	0.016
Neuromodulation	0.798 (0.304, 2.096)		0.647	—	0.016

IIQ (per each 10 points)
OnabotulinumtoxinA	0.866 (0.756, 0.992)		0.038	—	0.062
Neuromodulation	1.058 (0.898, 1.247)		0.499	—	0.062

Sandvik (per each 1 point)	0.835 (0.762, 0.916)		<0.001	—	—

A multivariable logistic regression model was used for analysis. Age category and an age-category-by-treatment-group interaction term were included in the multivariable model irrespective of p-value. For other predictors and interactions, terms were selected by backwards selection subject to p < 0.1, as described in Methods. Odds ratios represent the increased odds of a ≥75% reduction in UUI episodes associated with a unit increase in the predictor.