Figure 6.

Effect of bafilomycin A1 on artificial decidualization detected on pseudopregnant D7.5 WT mice. Artificial decidualization was induced by intraluminal oil injection on right side and bafilomycin A1 treatment was also on the right side via uterine fat pad injection. (A–D) Representative uteri from vehicle (A, B) or bafilomycin A1 injection (C, D). A and C shows decidualization on both uterine horns due to oil leakage from the right side. (E–G) Detection of decidualization marker Abp1 on right uterine horns by in situ hybridization. E from B; F from C; G from D; Scale bar, 200 μm. (H) Weight of right uterine horn (injected side). Error bar, standard deviation; N = 4; ^*P < 0.05.