Table 5.
Differentially expressed genes in the TP53 signaling network.
| Gene symbol | Average expression of genes in PTB placentae | Average expression of genes in term placentae | Log fold change (PTB vs term) | Unadjusted P-values* | Adjusted P-values** |
|---|---|---|---|---|---|
| RRM2B | 6.99 | 7.19 | –0.20 | 5 × 10−6 | 0.00025 |
| DDB2 | 6.44 | 6.55 | –0.10 | 0.0029 | 0.076 |
| SESN3 | 7.43 | 7.63 | –0.20 | 0.011 | 0.19 |
| CCNB1 | 6.14 | 6.01 | 0.13 | 0.019 | 0.25 |
| CASP3 | 7.40 | 7.49 | –0.09 | 0.025 | 0.27 |
| SERPINE1 | 10.79 | 10.56 | 0.22 | 0.031 | 0.27 |
| CCNB3 | 4.95 | 5.01 | –0.06 | 0.042 | 0.32 |
| ZMAT3 | 6.71 | 6.80 | –0.09 | 0.049 | 0.32 |
*T-test, unadjusted P < 0.05 ** Benjamini–Hochberg correction P < 0.05.