Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 17;96(5):1071–1084. doi: 10.1093/biolre/iox025

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Authors 2017. Published by Oxford University Press on behalf of Society for the Study of Reproduction.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 5. — Normal and representative severe histological lesions in the placenta. Low magnification images of control (top) and Nic + MP (bottom) placental disks with boxed areas indicating select sites subject to scoring: choriodecidua (boxes A and B), subchorion (boxes C and D), chorionic plate (boxes E and F), and visceral yolk sac (boxes G and H). Boxes correspond to the location of the structures shown in the high magnification image panels (control: A, C, E, G; Nic + MP: B, D, F, H). Arrows indicate neutrophils. Panel A shows normal choriodecidua. In Panel B, the decidua is obliterated by neutrophil infiltrates. Panel C shows normal subchorion. In Panel D, neutrophils infiltrate the maternal blood spaces at the periphery of the labyrinth zone. Panel E shows normal chorionic plate. Panel F shows epithelial effacement, neutrophil infiltration, and structural breakdown of the chorionic plate. Panel G shows normal visceral yolk sac. In Panel H, purulent exudate is seen among the endodermal villi of the visceral yolk sac. All images were obtained with an EVOS Auto FL imaging system (Life Technologies). Panels represent ×10 (A and B) or ×20 magnification. All scale bars are equivalent to 200 μm. Structural abbreviations: decidua (D), maternal blood sinus (MBS), trophoblastic giant cell (TGC), spongiotrophoblast (ST), labyrinth zone (LZ), Reichert's membrane (RM), intraplacental yolk sac (IPY), chorionic plate (CP), chorionic vessel (CV), endoderm (E), vitelline blood vessel (VBV), and mesothelium (M).