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. 2018 Feb 7;18:19. doi: 10.1186/s12903-018-0475-9

Table 1.

Eligibility criteria

Patients will be eligible for the study if they meet the following criteria:
- Boys or girls aged 12 to 16.
- For at least 6 weeks, they must have maxillary and mandibular fixed orthodontic appliance therapy, which consists of bonding at least premolar-to-premolar with edgewise appliances and their modifications.
- They have not been scheduled for removal of fixed orthodontic treatment before the end of the study.
- They have no physical and/or mental disabilities that will impede their ability to perform their own oral hygiene activities.
- They are not engaged in other oral-health education or research program.
- They do not have enamel and dentine dysplasia and/or craniofacial malformation (e.g. cleft).
- They have a sufficient command of the Dutch language.
- They possess a smartphone with software IOS ≥7 or Android ≥4.1.
- Patients and their parents are able or willing to give informed consent.
- Patients must not use medication that may affect plaque accumulation, for example antibiotics and antibacterial mouth rinses.