. 2018 Feb 7;18:33. doi: 10.1186/s12886-018-0700-y

Table 2.

The changes of VAS, TMH, FBUT and ABUT after treatment in the WMCGs and the 0.1% SH groups

	WMCG group (N = 22)		0.1% SH group (N = 18)
	Mean ± SD	P*	Mean ± SD	P*	P**
VAS
Pre-treatment	5.25 ± 2.00	N/A	5.07 ± 1.98	N/A	0.800
5 min post-treatment	1.68 ± 1.79	<0.001	4.26 ± 2.02	0.006	<0.001
30 min post-treatment	2.80 ± 1.96	<0.001	4.51 ± 1.83	0.017	0.015
60 min post-treatment	2.76 ± 1.84^a	<0.001	4.60 ± 1.69	0.058	0.005
TMH
Pre-treatment	0.18 ± 0.05	N/A	0.18 ± 0.05	N/A	0.701
5 min post-treatment	0.20 ± 0.06	0.004	0.21 ± 0.05	0.001	0.642
30 min post-treatment	0.21 ± 0.07	0.001	0.19 ± 0.05	0.275	0.341
60 min post-treatment	0.20 ± 0.06	0.012	0.18 ± 0.05	0.927	0.524
FBUT
Pre-treatment	3.49 ± 0.97	N/A	3.52 ± 1.22	N/A	0.936
5 min post-treatment	10.20 ± 7.21	<0.001	5.10 ± 1.76	0.011	0.004
30 min post-treatment	6.06 ± 2.85^a	0.001	5.74 ± 3.93	0.077	0.783
60 min post-treatment	6.34 ± 3.69^a	0.001	3.87 ± 1.26	0.463	0.007
ABUT
Pre-treatment	4.86 ± 1.34	N/A	4.92 ± 1.69	N/A	0.890
5 min post-treatment	14.29 ± 6.38	<0.001	6.86 ± 2.28	0.004	<0.001
30 min post-treatment	8.83 ± 4.31^a	0.002	6.98 ± 4.29	0.069	0.228
60 min post-treatment	8.05 ± 3.89^a	0.001	5.22 ± 1.60	0.566	0.015

P<0.05 was regarded as significant difference

VAS visual analog scale, TMH tear meniscus height, FBUT first break-up time, ABUT average break-up time, WMCGs warming moist chamber goggles, SH sodium hyaluronate

*Self-comparison (post-treatment values compared with baseline level) by paired t test with Bonferroni correction

**Comparison between the two groups at the same timepoint by independent t test

^aComparison between the value at 30 or 60 min and at 5 min after treatment