Table 5.
Structural MRI (HC/nonNPSLE/NPSLE patients)
| Mean | p value | ||||
|---|---|---|---|---|---|
| NonNPSLE patients (n = 25) | NPSLE patients (n = 39) | HC/nonNPSLE | HC/NPSLE | NonNPSLE/NPSLE | |
| Contrast-enhanced lesions | 0 | 0.4 | 1.0 | 0.203 | 0.183 |
| Ischemic lesions | 0.04 | 0.03 | 0.397 | 0.535 | 0.750 |
| Microhemorrhages | 0 | 0.05 | 1.0 | 0.219 | 0.188 |
| Level of atrophy | 0.04 | 0.1 | 0.640 | 0.193 | 0.393 |
| WMHI | 0.88 | 0.77 | 0.015* | 0.023* | 0.682 |
| ICH | 0 | 0 | - | - | - |
Characteristics of patients and controls in the cohort after exclusions. Healthy controls (n = 20); nonNPSLE patients (n = 25); NPSLE patients (n = 39)
MRI magnetic resonance imaging, HC healthy controls, NPSLE neuropsychiatric systemic lupus erythematosus, WMHI white matter hyperintensities, ICH intracerebral hemorrhage
*p < 0.05
**p < 0.01