Table 1.
Main characteristics of patients
| Characteristics | Responders n = 28 |
Non-responders n = 22 |
|---|---|---|
| Age (years) | 54 ± 13 | 53 ± 14 |
| Sex, male/female (n) | 16/12 | 10/12 |
| Height (cm) | 170 ± 9 | 169 ± 10 |
| Weight (kg) | 77 ± 15 | 72 ± 17 |
| SAPS II | 46 ± 17 | 46 ± 14 |
| Tidal volume (mL.kg-1 of predicted body weight) | 6.9 ± 0.7 | 6.8 ± 0.8 |
| Respiratory rate (breath.min-1) | 17 ± 5 | 16 ± 3 |
| Positive end-expiratory pressure (cmH2O) | 6 ± 2 | 6 ± 1 |
| Driving pressure (cmH2O) | 10 ± 3 | 10 ± 4 |
| Compliance of the respiratory system (mL/cmH2O) | 49 ± 17 | 51 ± 18 |
| PaO2/FiO2 | 294 ± 125 | 300 ± 126 |
| Etiology of disease on ICU admission | ||
| Subarachnoid hemorrhage (n) | 14 | 12 |
| Intracerebral hemorrhage (n) | 5 | 6 |
| Ischemic stroke (n) | 5 | 1 |
| Other (n) | 4 | 3 |
| Etiology of volume expansion | ||
| Need to increase mean arterial pressure (n) | 19 | 12 |
| Oliguria (n) | 2 | 7 |
| Tachycardia (n) | 7 | 3 |
| Left ventricular ejection fraction (%) | 55 ± 9 | 56 ± 9 |
| Norepinephrine (n (%)) | 25 (89%) | 22 (100%) |
| Dosage of norepinephrine (μg.kg-1.min-1) | 0.49 (0.19–1.5) | 0.90 (0.5–1.80) |
Values are mean ± SD, number of patients (n) or median (interquartile range (25–75%)) as appropriate
ICU Intensive Care Unit, SAPS II Simplified Acute Physiologic Score, PaO2/FiO2 ratio of arterial oxygen tension to inspired oxygen fraction