Fig. 5.

FL3 inhibits growth of UCB tumor xenografts in vivo. a The xenograft tumors were isolated from mice at the end of study. b Tumor volumes were recorded from the date of injection to the end of the study (mean, n = 7). c Histograms present the mean tumor weight in each group, means ± SD (n = 7). **P < 0.01, ***P < 0.001 indicates a significant difference between FL3-treated mice and control mice. d Tumors were embedded in paraffin and 5 μm thick sections were used for immunohistochemistry analysis with PHB or GADD45α antibody. e Body weights of mice were recorded along with the records of tumor volumes as dashed lines (mean, n = 7). f Main organs including heart, kidney, liver, and lung were removed from mice and embedded in paraffin for further hematoxylin eosin staining