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. 2018 Feb 5;5(1):ENEURO.0298-17.2017. doi: 10.1523/ENEURO.0298-17.2017

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Copyright © 2018 Kaya et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 8. — Expected fractional occupancy (or percentage saturation) of DA high-affinity receptors in response to successive releases. Fractional occupancy as a function of time is based on the probabilistic occurrence of saturation conditions ([DA]_local ≥ 10 nM) in the synaptic region associated with each AZ. Results are shown for different AZs (as labeled) in response to single release (A), two releases with 50-ms interspike interval (B), and four releases with 30-ms interspike intervals (C). Results from the VT model are shown for comparison in A and B.