. 2018 Mar;113(3):161–166. doi: 10.1590/0074-02760170281

TABLE. Fluorescence analysis in human macrophages infected with Mycobacterium tuberculosis after DNA breakage detection fluorescence in situ hybridisation (DBD-FISH) using a whole-genome DNA probe, biotin stain, and DAPI as a counterstain.

	Fluorescence analysis (DBD-FISH)
Group	Area (X ± SD)	Intensity(X ± SD)	ID (10⁴) (X ± SD)
Non-infected	601 ± 427⁺	150 ± 83⁺	9.01 ± 8.7⁺
Infected	2206 ± 942^* ⁺	176 ± 184^* ⁺	38.82 ± 46.7^* ⁺
Positive control	4221 ± 2739^*	157 ± 134^*	66.27 ± 58.2^*

^*:

a significant difference (p < 0.001) was observed with respect to uninfected macrophages.

^+:

a significant difference (p < 0.05) was observed with respect to positive control.