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. 2018 Feb 5;6:e4352. doi: 10.7717/peerj.4352

Table 3. ROC AUC values from the leave one out cross validation ROC AUC for assessing TdeP risk only across all data-sets for all models considered.

Leave One Out Cross Validation ROC AUC
Data-set 3 ion-channels hERG
Bnet ORD: ΔAPD90 TT: ΔAPD90 % Block IKr
Mirams et al. (2011) 0.78 0.66 0.75 0.62
Kramer et al. (2013) 0.86 0.80 0.84 0.68
Crumb Jr et al. (2016) 0.68 0.61 0.62 0.57
7 ion-channels
Crumb Jr et al. (2016) 0.77 0.63 0.59*

Notes.

*

based on six ion-channels—INaL not modelled by TenTusscher et al. (TT); ΔAPD90: percentage change in APD90.