Table 1.
Sensitivity, specificity, positive predictive value, and negative predictive value of BerEP4 in detecting BCC with SCC as control.
| Studies | BCC + | SCC + (control) |
|---|---|---|
| Karahan, et al. [16] | 20/20 | 0/20 |
| Fan, et al. [28] | 51/51 | - |
| Krahl & Sellheyer [29] | 28/28 | - |
| Ishida, et al. [30] | 20/20 | - |
| Filho, et al. [31] | 20/20 | - |
| Mashhood, et al. [32] | 29/29 | 0/11 |
| Tan & Sunjaya [9] | 23/23 | - |
| Kirzhner & Jakobiec [33] | 13/13 | - |
| Dasgeb, et al. [24] | 24/24 | 1/11 (weak positive) |
| Patil, et al. [12] | 9/9 | - |
| Sellheyer, et al. [34] | 17/17 | 0/75 |
| Ansai, et al. [35] | 30/31 | - |
| BerEP4 positive | 284 | 1 |
| Ber EP4 negative | 1 | 116 |
|
| ||
| Total | 285 | 117 |
|
| ||
| Sensitivity | 284/285 × 100 = 99.6% | |
| Specificity | 116/117 × 100 = 99.2% | |
| Positive predictive value | 284/285 × 100 = 99.6% | |
| Negative predictive value | 116/117 × 100 = 99.1% | |