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. Author manuscript; available in PMC: 2018 Feb 10.
Published in final edited form as: J Control Release. 2016 Dec 24;247:1–18. doi: 10.1016/j.jconrel.2016.12.021

Fig. 10. RNase treatment reduces the biological effect of MkMPs on HSPCs.

Fig. 10

Human CD34+ cells were cocultured with MkMPs (10 MkMPs/cell) treated with RNase (Ambion® RNase A/T1 cocktail or RNase ONE™) for 8 days before harvested for ploidy analysis by flow cytometry. (A) Numbers of Mk cells with different ploidy classes (2N, 4N, >=8N). (B) Numbers of total Mks and total cells. The data are represented as the averages of four biological replicates ± standard error of mean. *, P<0.05; **, P<0.01.