Figure 3:

associations between peri-adolescent HSD11B2 methylation and exposure biomarkers from multiple developmental stages. All estimates are from repeated measures models for HSD11B2 methylation at 4 CpG sites (from blood leukocyte DNA, PA study visit). Models adjust for children’s age and sex. All estimates give the change in % DNA methylation for an IQR range increase in the exposure biomarker (based on ln-transformed values for all biomarkers except for tibia and patella Pb). *Denotes significant association at the P  < 0.05 level. T3= trimester 3 (maternal samples).