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. Author manuscript; available in PMC: 2018 Feb 8.
Published in final edited form as: Vaccine. 2015 Mar 13;33(18):2152–2158. doi: 10.1016/j.vaccine.2015.03.009

Fig. 5.

Fig. 5

H7N9 VLP vaccine protection against virus shedding. Ferrets (6 per group) received two intramuscular inoculations (5 weeks apart) in the presence or absence of Matrix-M1 adjuvant and control animals received PBS in place of vaccine. Animals were challenged i.n. with 106 pfu of Anhui/1 virus. Nasal washes were collected prior to euthanasia (3 ferrets/time point) and titrated in a standard plaque assay. The differences in viral titers between groups were analyzed by two-way ANOVA. *p < 0.05, ***p < 0.001.