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. Author manuscript; available in PMC: 2018 Feb 8.
Published in final edited form as: J Biomed Mater Res A. 2016 Aug 11;104(12):3058–3072. doi: 10.1002/jbm.a.35850

Figure 6. Integrin expression by cardiac fibroblasts cultured within silk hydrogels.

Figure 6

A) 10 mE silk with and without cECM show an increase in integrin-linked kinase (ILK) expression over time. B) 30 mE silk with and without cECM show an increase in ILK expression as the samples stiffen, but the trend is more pronounced in samples containing cECM. C) Integrin β1 expression by cardiac fibroblasts in 10 mE hydrogels increases over time and in samples with cECM addition. D) Integrin B1 expression in 30 mE silk is higher in 4% silk samples containing cECM. Asterisk* indicates statistically greater protein expression compared to day 2 2% silk 0% cECM samples (p < 0.05). Pound symbol# indicates a significant increase in protein expression compared to day 2 4% silk 0% cECM samples (p < 0.05).