Fig 2.

A) Subgroup analyses on the primary outcome of a relative increase in serum creatinine 48–96 hours post intra-arterial contrast administration. Effect size is calculated as the difference in the mean relative increase in serum creatinine between both randomisation groups. B) Subgroup analyses on the secondary outcome of risk of contrast-induced acute kidney injury, calculated as relative risk. The straight line indicates the point estimate of the entire study population and the dashed line indicates no effect. Baseline creatinine clearance was calculated using the MDRD-formula.